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Results 1 - 7 of 7
EC Number
Application
Commentary
Reference
biotechnology
actinidin might be utilized to eliminate the milk fat globule membranes (MFGM) protein residues from cream and its derivatives
food industry
actinidin is used as a beef tenderizer, use of actinidin-tenderized beef significantly improves emulsion stability, texture, and organoleptic properties of the sausage product
medicine
actinidin is a biomarker of kiwifruit allergy
medicine
to isolate major kiwifruit allergens a large group of kiwi-sensitized patients with different clinical symptoms are investigated. The three major IgE-binding proteins from kiwifruit extracts are isolated and characterized. The isolated kiwifruit allergens are: actinidin Act d 1, glycosylated thaumatin-like Act d 2 and a novel 40 kDa glycoprotein designated as Act d 3.02. Specific IgE to each of the three allergens is found in over 60% of sera from kiwi-sensitized patients, and Act d 1 and Act d 2 induces positive SPT responses in over 50% of the tested patients. A significant link between IgE levels to Act d 1 and Act d 3 and anaphylaxis is uncovered. Act d 1, Act d 2 and Act d 3 are major allergens in the population studied. Severe symptoms after kiwi ingestion are associated with high IgE levels to Act d 1 and Act d 3
molecular biology
actinidin compared with type II or IV collagenase isolates intact human umbilical vein endothelial cells, hepatocytes, and thymic epithelial cells with viability more than 90%
nutrition
actinidin induces protease-dependent morphology changes of T84 human colorectal adenocarcinoma cells leading to cell rounding and desquamation of the epithelial monolayer, without affecting cell viability
synthesis
the enzyme can be used efficiently for hydrolysis of collagen and isolation of different cell populations from various solid tissues
Results 1 - 7 of 7