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medicine
the phosphatidylserine biosynthetic activity of brain, especially for 18:0, 22:6-phosphatidylserine production, is hampered significantly by maternal exposure to ethanol. Phosphatidylserine levels are consistently reduced significantly in brain cortices of the pups from ethanol-exposed dams, due mainly to the depletion of 18:0, 22:6-phosphatidylserine. The mRNA expression of phosphatidylserine synthase 1, EC 2.7.8.8, and PSS2 is not reduced by ethanol
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