EC Number   |
Natural Substrates |
|---|
   7.5.2.1 | ATP + H2O + maltose-[maltose-binding protein][side 1] |
- |
| 7.5.2.1 | ATP + H2O + maltose-[maltose-binding protein][side 1] + H+[side1] |
- |
| 7.5.2.1 | ATP + H2O + maltose/out |
- |
| 7.5.2.1 | ATP + H2O + maltose/out |
the peripheral membrane protein MalK associates with integral cytoplasmic membrane proteins MalF and MalG to form the maltose transport complex MalFGK. In addition malK participates in two different regulatory pathways which modulate mal gene expression and MalFGK transport activity |
| 7.5.2.1 | ATP + H2O + maltose/out |
translocation of maltose across biological membranes |
| 7.5.2.1 | ATP + H2O + maltose/out |
extracytoplasmic anchoring of the substrate binding protein, the receptor, is emerging as key determinant for the structural rearrangements in the cytoplasmically exposed ATP-binding cassette domains and in the transmembrane gates during the nucleotide cycle, molecular mechanism, overview |
| 7.5.2.1 | more |
interactions of MalK with the regulatory proteins MalT and enzyme IIAglc |
| 7.5.2.1 | more |
concomitantly with the three conformations of the ATP-binding cassette MalK2, three functionally relevant conformations are found also in the periplasmic MalF-P2 loop, strictly dependent on cytoplasmic nucleotide-binding and periplasmic docking of liganded MalE to MalFG, overview |
| 7.5.2.1 | more |
MalK is the ABC-ATPase of the maltose importer of Escherichia coli. The MalK accessory domain interacts with at least two enzymes, MalT and IIA |
| 7.5.2.1 | more |
the MalF P2 loop plays an important role in intersubunit communication. In particular, this loop is involved in keeping MalE in close contact with the transporter. the MalF P2 loop of the ATP-binding cassette transporter MalFGK2 interacts with maltose binding protein MalE throughout the catalytic cycle, overview |
