EC Number |
Natural Substrates |
---|
7.4.2.5 | ATP + H2O |
- |
7.4.2.5 | ATP + H2O |
ATP hydrolysis by SecA is required only if periplasmic loops larger than 30 amino acids have to be translocated. The signal recognition particle-dependent and SecA-dependent multiple spanning membrane protein YidC becomes SecA-independent if the large periplasmic loop connecting transmembrane domains 1 and 2 is reduced to less than 30 amino acids. The SecA dependence of a bacterial membrane protein is not solely determined by the length of the periplasmic loop but also by the presence of a down-stream TM domain |
7.4.2.5 | ATP + H2O |
ATPase SecA provides the driving force for the transport of secretory proteins across the cytoplasmic membrane of Escherichia coli |
7.4.2.5 | ATP + H2O |
SecA2 plays a role in Mycobacterium tuberculosis inhibition of the immune response, which is likely important for survival in the host and pathogenesis |
7.4.2.5 | ATP + H2O + aerolysin/in |
- |
7.4.2.5 | ATP + H2O + alpha-haemolysin/in |
- |
7.4.2.5 | ATP + H2O + formyl-methionyl-leucine-phenylalanine/in |
- |
7.4.2.5 | ATP + H2O + hemoprotein HasA/in |
- |
7.4.2.5 | ATP + H2O + L-Ala-gamma-D-Glu-meso-diaminopimelic acid/in |
- |
7.4.2.5 | ATP + H2O + lacticin 481/in |
lactococcal bacteriocin |