EC Number |
Natural Substrates |
---|
6.3.5.6 | Asp-tRNAAsn + ? |
- |
6.3.5.6 | Asp-tRNAAsn + ? |
in vivo only Asn-tRNAAsn formation occurs, since Thermus possesses a mischarging Asp-tRNA synthetase, but lacks a mischarging Glu-tRNA synthetase, and cellular activity of AdTs only depends upon presence or lack of the mischarging amino acyl-tRNA synthetases, explaining why those enzymes have not restricted their specificity |
6.3.5.6 | Asp-tRNAAsn + ? |
tRNA-dependent transamidation pathway of Asn-tRNA formation, which is required for protein synthesis or under certain metabolic situations for asparagine synthesis |
6.3.5.6 | Asp-tRNAAsn + ? |
AdT is related to the biosynthesis of asparagine rather than to provide charged tRNA for protein biosynthesis |
6.3.5.6 | Asp-tRNAAsn + ? |
tRNA-dependent transamidation pathway of Asn-tRNA formation, only biosynthetic route to asparagine is via Asn-tRNA |
6.3.5.6 | Asp-tRNAAsn + ? |
the mischarging Asp-tRNA synthetase correlates with the absence in the genome of Asn-tRNA synthetase and the presence of Asp-tRNAAsn amidotransferase, employed by the transamidation pathway |
6.3.5.6 | Asp-tRNAAsn + ? |
gatCAB genes encoded Asp-AdT may be responsible for biosynthesis of asparagine, glutamine as amide source |
6.3.5.6 | Asp-tRNAAsn + ? |
it is likely that the dual specificity amidotransferase serves in Asn-tRNA and Gln-tRNA formation in vivo |
6.3.5.6 | Asp-tRNAAsn + ? |
in vivo only Asn-tRNAAsn formation occurs |
6.3.5.6 | Asp-tRNAAsn + ? |
enzyme of the two-step pathway for the synthesis of Asn-tRNA that requires misacylated Asp-tRNAAsn as intermediate, which is generated by a Asp-tRNA synthetase |