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Results 1 - 4 of 4

EC Number	Natural Substrates	Commentary (Nat. Sub.)
6.3.4.19	[tRNAIle2]-cytidine34 + L-lysine + ATP	-
6.3.4.19	[tRNAIle2]-cytidine34 + L-lysine + ATP	bacteria decode the isoleucine codon AUA using a tRNA species that is posttranscriptionally modified at the wobble position of the anticodon with a lysine-containing cytidine derivative called lysidine. The lysidine modification of tRNAIle2 is an essential identity determinant for proper aminoacylation by isoleucyl tRNA synthetase and codon recognition on the ribosome. The ATP- and lysine-dependent formation of lysidine is catalyzed by tRNAIle-lysidine synthetase
6.3.4.19	[tRNAIle2]-cytidine34 + L-lysine + ATP	enzyme catalyzes the lysylation of C34 (wobble position) in the precursor tRNAIle(CAU), thereby leading to the formation of tRNAIle(lysidineAU). The formation of lysidine by this essential enzyme allows recognition of tRNAIle(lysidineCAU) by Ile-tRNA synthetase and switches the base pairing of the tRNA from AUG (Met) to AUA (Ile)
6.3.4.19	[tRNAIle2]-cytidine34 + L-lysine + ATP	the enzyme generates lysidine at the wobble position of tRNAIle. The enzyme is essential for the decoding of AUA codons in the cell

Results 1 - 4 of 4

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Release 2023.1 (January 2023)