EC Number   |
Natural Substrates |
|---|
   6.3.2.14 | 6 ATP + 3 2,3-dihydroxybenzoate + 3 L-serine |
overall reaction. EntB, -D, -E, and -F are then required to catalyze the ATP-dependent assembly of enterobactin from three molecules each of 2,3-dihydroxybenzoate and L-serine. EntD, a phosphopantetheinyl transferase, uses coenzyme A to phosphopantetheinylate S245 of the aryl carrier protein domain of EntB. Next, EntE catalyzes the transfer of 2,3-dihydroxybenzoate onto the phosphopantetheinylated (holo) EntB to yield the covalently arylated EntB. Finally, arylated EntB, ATP, and L-serine are used as substrates for the reaction catalyzed by EntF to generate enterobactin |
| 6.3.2.14 | 6 ATP + 3 2,3-dihydroxybenzoate + 3 L-serine |
overall reaction. EntB, -D, -E, and -F are then required to catalyze the ATP-dependent assembly of enterobactin from three molecules each of 2,3-dihydroxybenzoate and L-serine. EntD, a phosphopantetheinyl transferase, uses coenzyme A to phosphopantetheinylate S245 of the aryl carrier protein domain of EntB. Next, EntE catalyzes the transfer of 2,3-dihydroxybenzoate onto the phosphopantetheinylated (holo)EntB to yield the covalently arylated EntB. Finally, arylated EntB, ATP, and L-serine are used as substrates for the reaction catalyzed by EntF to generate enterobactin |
| 6.3.2.14 | ATP + 2,3-dihydroxybenzoate + L-serine |
component of enterobactin synthetase activity that specifically transfers the dihydroxybenzoate acyl group onto holo-entB |
| 6.3.2.14 | ATP + 2,3-dihydroxybenzoate + phosphopantetheinylated EntB |
reaction of EntE |
| 6.3.2.14 | ATP + arylated EntB + L-serine |
reaction of EntF |
