EC Number   |
Natural Substrates |
|---|
    6.2.1.5 | ADP + phosphate + succinyl-CoA |
- |
| 6.2.1.5 | ADP + phosphate + succinyl-CoA |
generation of ATP is critical for the beta-cell mitochondrial metabolism |
| 6.2.1.5 | ADP + phosphate + succinyl-CoA |
the enzyme carries out the substrate-level phosphorylation in the citric acid cycle |
| 6.2.1.5 | ADP + phosphate + succinyl-CoA |
the enzyme plays an essential role in the citric acid cycle, where the conversion of succinyl-CoA into succinate represents an important site of substrate level phosphorylation |
| 6.2.1.5 | ADP + phosphate + succinyl-CoA |
catalyzes the formation of ATP via substrate-level phosphorylation |
| 6.2.1.5 | ATP + acetate + CoA |
- |
| 6.2.1.5 | ATP + acetate + CoA |
Blastocystis succinyl-CoA synthetase is a tricarboxylic acid cycle enzyme that conserves energy by substrate-level phosphorylation. In the absence of a classic mitochondrial electron transport chain, it is likely to be one of the main ATP producing enzymes in this parasite |
| 6.2.1.5 | ATP + itaconate + CoA |
- |
| 6.2.1.5 | ATP + succinate + CoA |
- |
| 6.2.1.5 | ATP + succinate + CoA |
AarC is succinyl-CoA:acetate CoA-transferase, which replaces succinyl-CoA synthetase in a variant CAC, this new bypass appears to reduce metabolic demand for free CoA, reliance upon nucleotide pools, and the likely effect of variable cytoplasmic pH upon CAC flux, the enzyme is required for the citric acid cycle, overview |
