EC Number   |
Natural Substrates |
|---|
   5.6.2.1 | more |
- |
| 5.6.2.1 | more |
may participate in recombination events |
| 5.6.2.1 | more |
provides a swivel during replication |
| 5.6.2.1 | more |
DNA structural alterations induced by UV lesions can be sufficient stimulus to induce cross-linking of topoisomerase I to cellular DNA |
| 5.6.2.1 | more |
enzyme controls repair function |
| 5.6.2.1 | more |
role in control of DNA topology including regulation of supercoiling and maintenance of genetic stability |
| 5.6.2.1 | more |
controls the DNA topology by cleaving and rejoining DNA strands and passing other DNA strands through the transient gaps, plays a crucial role in the regulation of the physiological function of the genome |
| 5.6.2.1 | more |
topoisomerase I works in concert with topoisomerase II to modulate the level of DNA supercoiling |
| 5.6.2.1 | more |
probably engaged in the assembly of chromatin |
| 5.6.2.1 | more |
enzyme controls the topological state of DNA |
