EC Number   |
Natural Substrates |
|---|
   5.6.1.7 | ADP + H2O + a folded polypeptide |
- |
| 5.6.1.7 | ADP + phosphate + unfolded actin |
- |
| 5.6.1.7 | ADP + phosphate + unfolded tubulin |
- |
| 5.6.1.7 | ATP + H2O + a folded polypeptide |
- |
| 5.6.1.7 | ATP + H2O + a folded polypeptide |
GroEL participates in bacterial temperature adaption |
| 5.6.1.7 | ATP + H2O + a folded polypeptide |
the archaeal GroEL/GroES system has preserved the basic encapsulation mechanism of bacterial GroEL and suggest that it has adjusted the length of its reaction cycle to the slower growth rates of Archaea. The release of only folded protein from the GroEL/GroES cage would avoid non-productive interactions of the GroEL substrates with the thermosome, which is not normally located within the same compartment |
| 5.6.1.7 | ATP + H2O + a folded polypeptide |
aconitase B, bind transiently to GroEL and probably doesn´t require ATP and GroES |
| 5.6.1.7 | ATP + H2O + a folded polypeptide |
bovine rhodanese |
| 5.6.1.7 | ATP + H2O + a folded polypeptide |
MetE, bind transiently to GroEL and probably doesn´t require ATP and GroES |
| 5.6.1.7 | ATP + H2O + a folded polypeptide |
pig heart malate dehydrogenase |
