EC Number   |
Natural Substrates |
|---|
    5.3.3.1 | 5-Androstene-3,17-dione |
- |
| 5.3.3.1 | a 3-oxo-DELTA5-steroid |
- |
| 5.3.3.1 | more |
in pregnancy placental 3beta-hydroxy-5-ene-steroid dehydrogenase and steroid 5--4 isomerase produce progesterone from pregnenolone and metabolize fetal dehydroepiandrosterone sulfate to androstenedione, an estrogen precursor |
| 5.3.3.1 | more |
enzyme can be induced by various steroids |
| 5.3.3.1 | more |
the conversion of 3beta-hydroxy-5-ene steroids by the enzyme complex 3beta-hydroxysteroid dehydrogenase/DELTA5-DELTA4 isomerase is an obligatory step in the biosynthesis of all classes of hormonal steroids in classical steroidogenic as well as in peripheral tissues |
| 5.3.3.1 | more |
the bifunctional enzyme possesses 3beta-hydroxysteroid dehydrogenase activity, EC 1.1.1.51, and steroid DELTA-isomerase activity, the enzyme is a key steroidogenic enzyme that catalyzes the first step of the multienzyme pathway conversion of circulating dehydroepiandrosterone and pregnenolone to active steroid hormones |
| 5.3.3.1 | more |
the enzyme is involved in synthesis of sex steroids influencing the development and function of the songbird brain, overview |
