EC Number |
Natural Substrates |
---|
5.3.1.28 | D-sedoheptulose 7-phosphate |
first step of the biosynthesis of the inner core lipopolysaccharide precursor, ADP-L-glycero-D-manno-heptose |
5.3.1.28 | D-sedoheptulose 7-phosphate |
synthesis of ADP-D-beta-D-heptose in Escherichia coli requires three proteins, GmhA (sedoheptulose 7-phosphate isomerase), HldE (bifunctional D-beta-D-heptose 7-phosphate kinase/D-beta-D-heptose 1-phosphate adenylyltransferase), and GmhB (D,D-heptose 1,7-bisphosphate phosphatase) |
5.3.1.28 | D-sedoheptulose 7-phosphate |
- |
5.3.1.28 | D-sedoheptulose 7-phosphate |
first committed step in the formation of ADP-heptose |
5.3.1.28 | D-sedoheptulose 7-phosphate |
the enzyme is involved in the biosynthesis of nucleotide-activated heptose |
5.3.1.28 | more |
the gmhA gene product is essential for the expression of wild-type lipooligosaccharide by this pathogen |