EC Number |
Natural Substrates |
---|
5.1.3.17 | heparosan N-sulfate D-glucuronate |
- |
5.1.3.17 | Heparosan-N-sulfate D-glucuronate |
- |
5.1.3.17 | Heparosan-N-sulfate D-glucuronate |
C5-epimerization is irreversible in vivo |
5.1.3.17 | Heparosan-N-sulfate D-glucuronate |
the enzyme controle heparan sulfate chain flexibility, its activity, modifiying the substrate, is required for proper lymphoid organ development, overview |
5.1.3.17 | more |
enzyme catalyzes formation of L-iduronic acid residues in the course of heparin biosynthesis |
5.1.3.17 | more |
L-iduronosyl moieties are formed after N-sulfation but before O-sulfation |
5.1.3.17 | more |
enzyme is involved in the biosynthesis of heparan sulfate in liver |
5.1.3.17 | more |
limiting factor in dermatan sulfate biosynthesis |
5.1.3.17 | more |
the enzyme is involved in the biosynthesis of heparin and heparan sulfate |
5.1.3.17 | more |
key heparan sulfate modifying enzyme, a biosynthetic step that enhances biological activity of heparan sulfate. The enzyme is an important determinant of dorso-ventral axis formation and patterning in zebrafish |