EC Number |
Natural Substrates |
---|
4.6.1.2 | GTP |
- |
4.6.1.2 | GTP |
the guanylyl cyclase messenger system is potentially responsive to hormones/neurotranmitters that may control the degree of relaxation in this vascular tissue |
4.6.1.2 | GTP |
atrial natriuretic factor receptor guanylate cyclase GC-A is the receptor of the atrial natriuretic factor and the type B natriuretic peptide, overview |
4.6.1.2 | GTP |
cGMP levels in response to relaxant agonists are regulated in gastrointestinal smooth muscle by activation of phosphodiesterase 5 and inhibition of soluble guanylyl cyclase by c-Src-dependent phosphorylation in a feedback mechanism via the cGMP-dependent protein kinase, mechanism for attenuation of the NO/sGC/cGMP signal by Gi-coupled contractile agonists, overview |
4.6.1.2 | GTP |
desensitization of the soluble guanylyl cyclase/cGMP pathway by lipopolysaccharide in rat isolated pulmonary artery but not aorta, leading to muscle relaxation |
4.6.1.2 | GTP |
GC-A acts as receptor for atrial natriuretic peptide that regulates arterial blood pressure and volume, overview |
4.6.1.2 | GTP |
GTP is a chemorepellent in Tetrahymena thermophila that stimulates cell division as well as ciliary reversal. Protein kinase C activy is not required for GTP signaling |
4.6.1.2 | GTP |
guanylyl cyclase receptors synthesize the second-messenger cyclic GMP |
4.6.1.2 | GTP |
guanylyl cyclase-C is a peptide hormone receptor |
4.6.1.2 | GTP |
in the heart exists a coupled multienzymatic system for selective regulation of indirect, sGC-dependent versus direct, sGC-independent NO- and redox-related modulation of voltage-gated ion channel function in different myocyte types, mechanisms, overview |