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EC Number
Natural Substrates
Commentary (Nat. Sub.)
4.4.1.17
Apocytochrome c + heme
-
4.4.1.17
Apocytochrome c + heme
during its import into mitochondria
4.4.1.17
Apocytochrome c + heme
enzyme for the covalent attachment of heme to apocytochrome c
4.4.1.17
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during apoptotic stimuli, enzyme translocates to outside the mitochondria, and binds to and suppresses the X-linked inhibitor of apoptosis protein XIAP, leading to activation of caspase-3. The N-terminus of the neuronal glutamate transporter excitatory amino-acid carrier 1 EAAC1 can bind to enzyme which interferes with the enzyme-XIAP association
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