EC Number   |
Natural Substrates |
|---|
   4.3.3.2 | 3-alpha(S)-strictosidine + H2O |
- |
| 4.3.3.2 | tryptamine + secologanin |
- |
| 4.3.3.2 | tryptamine + secologanin |
higher activity in dark grown than in light grown cultures |
| 4.3.3.2 | tryptamine + secologanin |
involved in synthesis of monoterpenoid indole alkaloides |
| 4.3.3.2 | tryptamine + secologanin |
the strictosidine synthase catalyzes the condensation of tryptamine and secologanin to form strictosidine, which is the universal precursor for a wide range of pharmaceutical terpenoid indole alkaloids, TIA, e.g. in biosynthesis of reserpine and ajmalicine from the Chinese native TIAs-producing plant, overview |
| 4.3.3.2 | tryptamine + secologanin |
the strictosidine synthase plays a central role in the biosynthesis of all structural types of monoterpenoid indole alkaloids, overview |
| 4.3.3.2 | tryptamine + secologanin |
the enzyme is as amine lyases and catalyzes a PictetSpengler-type condensation between tryptamine and the aldehyde secologanin which leads to the formation of (S)-strictosidine |
