EC Number   |
Natural Substrates |
|---|
    4.2.1.78 | 4-(2-Aminoethyl)benzene-1,2-diol + 4-hydroxyphenylacetaldehyde |
- |
| 4.2.1.78 | 4-(2-Aminoethyl)benzene-1,2-diol + 4-hydroxyphenylacetaldehyde |
first step of benzylisoquinoline alkaloid synthesis, enzyme might play a regulatory or rate-limiting role in controlling the rate of pathway flux |
| 4.2.1.78 | 4-(2-Aminoethyl)benzene-1,2-diol + 4-hydroxyphenylacetaldehyde |
the enzyme is involved in the plantยs secondary metabolism and is required for the production of bioactive secondary metabolites like morphine |
| 4.2.1.78 | 4-(2-Aminoethyl)benzene-1,2-diol + 4-hydroxyphenylacetaldehyde |
initial reaction in isoquinoline biosynthesis |
| 4.2.1.78 | 4-hydroxyphenylacetaldehyde + 4-(2-aminoethyl)benzene-1,2-diol |
4-(2-aminoethyl)benzene-1,2-diol, i.e. dopamine |
| 4.2.1.78 | 4-hydroxyphenylacetaldehyde + 4-(2-aminoethyl)benzene-1,2-diol |
stereospecific formation of the (S)-norcolaurine enantiomer by the recombinant enzyme, overview |
| 4.2.1.78 | 4-hydroxyphenylacetaldehyde + dopamine |
- |
| 4.2.1.78 | 4-hydroxyphenylacetaldehyde + dopamine |
60% conversion after 3 h |
| 4.2.1.78 | 4-hydroxyphenylacetaldehyde + dopamine |
the enzyme catalyzes the enantioselective Pictet-Spengler condensation of dopamine and 4-hydroxyphenylacetaldehyde as a step in benzylisoquinoline alkaloid biosynthesis |
| 4.2.1.78 | 4-hydroxyphenylacetaldehyde + dopamine |
the enzyme catalyzes the stereoselective Pictet-Spengler reaction between dopamine and 4-hydroxyphenylacetaldehyde as a step of benzylisoquinoline alkaloid synthesis in plants |
