EC Number |
Natural Substrates |
---|
4.2.1.3 | (Z)-2-methylaconitate |
the enzyme is involved in the methylcitric acid cycle |
4.2.1.3 | (Z)-2-methylaconitate + H2O |
enzyme is involved in pathway of oxidation of propionate to pyruvate |
4.2.1.3 | cis-aconitate + H2O |
- |
4.2.1.3 | cis-aconitate + H2O |
aconitase catalyzes a reversible isomerization of citrate into isocitrate in the Krebs cycle |
4.2.1.3 | citrate |
- |
4.2.1.3 | citrate |
aconitase catalyzes a reversible isomerization of citrate into isocitrate in the Krebs cycle |
4.2.1.3 | more |
one or more of the aconitases may contribute to the control of the synthesis of the virulence factor exotoxin A |
4.2.1.3 | more |
Mn2+ exposure leads to a region-specific alteration in total aconitase: 48.5% reduction of the enzyme activity in frontal cortex, 33.7% in striatum and 20.6% in substantia nigra. This leads to the disruption of mitochondrial energy production and cellular Fe metabolism in the brain |
4.2.1.3 | more |
inductively formed in presence of fluorocitrate |
4.2.1.3 | more |
aconitase B is the major isoenzyme which is synthesized earlier in the growth cycle than aconitase A and is subject to catabolite and anaerobic repression |