EC Number   |
Natural Substrates |
|---|
    4.2.1.22 | L-Serine + homocysteine |
- |
| 4.2.1.22 | L-Serine + homocysteine |
initial step in transsulfuration forming cysteine. Homocysteine is a relatively toxic amino acid, which levels have to be kept low |
| 4.2.1.22 | L-Serine + homocysteine |
synthesis of cystathionine |
| 4.2.1.22 | L-Serine + homocysteine |
reverse trans-sulfuration pathway |
| 4.2.1.22 | L-Serine + homocysteine |
irreversible step in transsulfuration pathway |
| 4.2.1.22 | L-Serine + homocysteine |
reduced activity of EC 4.2.1.22 in patients with homocystinuria due to mutations in the CBS gene |
| 4.2.1.22 | L-serine + L-homocysteine |
- |
| 4.2.1.22 | L-serine + L-homocysteine |
the enzyme participates in the process of oocyte maturation |
| 4.2.1.22 | more |
first step in transsulfuration pathway |
| 4.2.1.22 | more |
key enzyme involved in intracellular metabolism of homocysteine |
