EC Number   |
Natural Substrates |
|---|
    4.1.3.30 | (2S,3R)-3-Hydroxybutane-1,2,3-tricarboxylate |
one of the key enzymes of the methylcitrate cycle. Deletion mutants do not grow on propionate as sole carbon and energy source and are severely inhibited during growth on alternative carbon sources, when propionate is present. The strongest inhibitory effect is observed, when glycerol is the main carbon source, followed by glucose and acetate. In addition, asexual conidiation is strongly impaired in the presence of propionate |
| 4.1.3.30 | (2S,3R)-3-Hydroxybutane-1,2,3-tricarboxylate |
enzyme synthesis is repressed by glucose |
| 4.1.3.30 | (2S,3R)-3-Hydroxybutane-1,2,3-tricarboxylate |
enzyme of propionate catabolism |
| 4.1.3.30 | (2S,3R)-3-Hydroxybutane-1,2,3-tricarboxylate |
key enzyme in propionate metabolism |
| 4.1.3.30 | (2S,3R)-3-Hydroxybutane-1,2,3-tricarboxylate |
the enzyme may function to supply pyruvate, the end-product of the catabolism of the propionate residue, to various reactions |
| 4.1.3.30 | (2S,3R)-3-Hydroxybutane-1,2,3-tricarboxylate |
regulatory enzyme of the methylcitric acid cycle |
| 4.1.3.30 | (2S,3R)-3-hydroxybutane-1,2,3-tricarboxylate |
- |
| 4.1.3.30 | 2-methylisocitrate |
the enzyme is involved in the methylcitric acid cycle |
| 4.1.3.30 | more |
enzyme in methylcitrate cycle |
| 4.1.3.30 | more |
Mycobacterium tuberculosis isocitrate lyases are catalytically bifunctional isocitrate and methylisocitrate lyases, EC 4.1.3.1 and EC 4.1.3.30, required for growth on even and odd chain fatty acids |
