EC Number   |
Natural Substrates |
|---|
   3.6.1.62 | a 5'-(N7-methylguanosine 5'-triphospho)-[mRNA] + H2O |
- |
| 3.6.1.62 | m7G5'ppp5'-mRNA + H2O |
- |
| 3.6.1.62 | m7G5'ppp5'-mRNA + H2O |
D9 is expressed early in infection and D10 late. It is suggested that the two proteins enhance mRNA turnover and manipulate gene expression in a complementary and overlapping manner |
| 3.6.1.62 | m7G5'ppp5'-mRNA + H2O |
DCP2 and the interacting proteins DCP1, and VCS form a decapping complex in vivo. mRNA turnover mediated by the decapping complex is required for postembryonic development in Arabidopsis |
| 3.6.1.62 | m7G5'ppp5'-mRNA + H2O |
Dcp2 has role in mRNA decay |
| 3.6.1.62 | m7G5'ppp5'-mRNA + H2O |
Dcp2 is involved in mRNA decay |
| 3.6.1.62 | m7G5'ppp5'-mRNA + H2O |
decapping of mRNA is a critical step in eukaryotic mRNA turnover |
| 3.6.1.62 | m7G5'ppp5'-mRNA + H2O |
hNUDT16 relies on divalent cations for its cap-hydrolysis activity to remove m7GDP and m227GDP from RNAs |
| 3.6.1.62 | m7G5'ppp5'-mRNA + H2O |
mRNA decapping is a critical step in the control of mRNA stability and gene expression |
| 3.6.1.62 | m7G5'ppp5'-mRNA + H2O |
regulation of RNA degradation plays an important role in the control of gene expression. Mammalian cells possess multiple mRNA decapping enzymes to regulate mRNA turnover. Nudt16, like Dcp2, is involved in mRNA stability. Each decapping enzyme can selectively affect the stability of at least a subset of mRNAs |
