EC Number   |
Natural Substrates |
|---|
  3.6.1.57 | UDP-2,4-diacetamido-2,4,6-trideoxy-beta-L-altropyranose + H2O |
- |
| 3.6.1.57 | UDP-2,4-diacetamido-2,4,6-trideoxy-beta-L-altropyranose + H2O |
the enzyme is involved in biosynthesis of pseudaminic acid (i.e. 5,7-diacetamido-3,5,7,9-tetradeoxy-L-glycero-alpha-L-manno-nonulosonic acid). Flagella of Campylobacter jejuni are important virulence determinants, whose proper assembly and function are dependent upon glycosylation at multiple positions by sialic acid-like sugars, such as 5,7-diacetamido-3,5,7,9-tetradeoxy-L-glycero-L-manno-nonulosonic acid (pseudaminic acid) |
| 3.6.1.57 | UDP-2,4-diacetamido-2,4,6-trideoxy-beta-L-altropyranose + H2O |
the enzyme is involved in biosynthesis of pseudaminic acid (i.e. 5,7-diacetamido-3,5,7,9-tetradeoxy-L-glycero-alpha-L-manno-nonulosonic acid). The large value of the specificity constant suggests that hydrolysis of UDP-2,4-diacetamido-2,4,6-trideoxy-beta-L-altropyranose is the biologically relevant reaction catalyzed by this enzyme |
