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EC Number
Natural Substrates
Commentary (Nat. Sub.)
3.5.4.5
2'-deoxycytidine + H2O
-
3.5.4.5
5-aza-2'-deoxycytidine + H2O
5-AZA-CdR shows an antineoplastic action on 3T3 cells and V5 cells transduced with CR deaminase gene, pharmakokinetic analysis in mice, overview
3.5.4.5
cytidine + H2O
-
3.5.4.5
cytidine + H2O
cytidine deaminase is a key enzyme in the catabolism of cytosine nucleoside analogues, since their deamination results in a loss of their pharmacological activity
3.5.4.5
cytosine arabinoside + H2O
-
3.5.4.5
cytosine beta-D-arabinofuranoside + H2O
-
3.5.4.5
deoxycytidine + H2O
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3.5.4.5
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cytidine deaminase plays an important role in the activation of the anticancer drug capesitabine in the human body
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