EC Number   |
Natural Substrates |
|---|
    3.5.4.10 | 5-formamido-1-(5-phospho-D-ribosyl)imidazole-4-carboxamide |
- |
| 3.5.4.10 | 5-formamido-1-(5-phospho-D-ribosyl)imidazole-4-carboxamide |
the enzyme catalyze the final step of de novo purine biosynthesis |
| 3.5.4.10 | 5-formamido-1-(5-phosphoribosyl)imidazole-4-carboxamide |
de novo purine synthesis step 10 |
| 3.5.4.10 | 5-formamido-1-(5-phosphoribosyl)imidazole-4-carboxamide + H2O |
catalyzation of the final two steps of de novo purine biosynthesis pathway |
| 3.5.4.10 | more |
bifunctional enzyme aminoimidazole-comprising the 4-carboxamide ribonucleotide transformylase, AICAR or Tfase, residues 200-593 and the IMPCH, ATIC, activities and catalyzes the final step in the de novo purine biosynthesis pathway that produces IMP, overview |
| 3.5.4.10 | more |
the TM1249 gene or gene purH of Thermotoga maritima encodes a bifunctional enzyme with 5-aminoimidazole-4-carboxamide ribonucleotide transformylase, AICAR Tfase, EC 2.1.2.3, and inosine 5'-monophosphate cyclohydrolase, IMPCH, EC 3.5.4.10, activities. These activities represent the final two steps of the de novo purine biosynthesis pathway, overview |
