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Results 1 - 10 of 12

EC Number	Natural Substrates	Commentary (Nat. Sub.)
3.4.24.26	casein + H2O	-
3.4.24.26	Elastin + H2O	-
3.4.24.26	Elastin + H2O	human tropoelastin
3.4.24.26	Fibronectin + H2O	-
3.4.24.26	flagellin + H2O	the enzyme is capable of degrading exogenous flagellin under calcium-replete conditions and prevents flagellin-mediated immune recognition
3.4.24.26	Gliadin + H2O	-
3.4.24.26	gluten + H2O	-
3.4.24.26	human thrombin + H2O	digestion of thrombin by Pseudomonas aeruginosa elastase leads to the release of the C-terminal thrombin-derived peptide FYT21, which inhibits pro-inflammatory responses to several pathogen-associated molecular patterns in vitro and in vivo by preventing toll-like receptor dimerization and subsequent activation of down-stream signalling pathways the enzyme cleaves a C-terminal peptide from human thrombin that inhibits host inflammatory responses
3.4.24.26	more	probably responsible for the tissue destruction observed during pulmonary and corneal infections by the pathogen organism Pseudomonas aeruginosa
3.4.24.26	more	pseudolysin eliminates epitopes recognized by the R5 antibody, while those detected by the G12 antibody remain intact, despite destruction of the nearby major T-cell epitope QPQLPY

Results 1 - 10 of 12

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Release 2023.1 (January 2023)