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EC Number
Natural Substrates
Commentary (Nat. Sub.)
3.4.24.25
aminopeptidase + H2O
vibriolysin activates aminopeptidase
3.4.24.25
HlyA protein + H2O
the enzyme degrades HlyA to diminish Vibrio cholerae hemolytic activity
3.4.24.25
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isolated proteinase MvP1 is non-lethal to salmon at concentrations up to 0.22 microg/g fish. It causes considerable tissue necrosis and hemorrhages at the site of injection, and affects cell-cell adhesions in EPC and BF-2 cell lines, but is not highly cytotoxic. The peptidase partially degrades fish IgM heavy chain but is non-hemolytic
3.4.24.25
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treatment of Salmo salar macrophage-like cell line SHK-1 cell with peptidase MvP1 does not cause cell death. In SHK-1 cells, isolated MvP1 peptidase stimulates both interleukin 1beta and interleukin 8 expression
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