EC Number   |
Natural Substrates |
|---|
   3.4.23.25 | lipid transfer protein 1 + H2O |
- |
| 3.4.23.25 | more |
protein degradation under sporulation conditions is about 30% reduced in proteinase A mutant cells, the differentiation process of sporulation is also disturbed leading to a 40% reduced sporulation frequency in mutant cells |
| 3.4.23.25 | more |
involved in intracellular proteolysis, especially under sporulation conditions |
| 3.4.23.25 | more |
essential to the activities of other yeast vacuolar hydrolases, including proteinase B, aminopeptidase I, and carboxypeptidase Y |
| 3.4.23.25 | more |
important for protein turnover after oxidative damage, supplies nitrogen under nutritional stress conditions |
| 3.4.23.25 | more |
required for the activation of carboxypeptidase Y and proteinase B |
| 3.4.23.25 | procarboxypeptidase Y + H2O |
maturation and activation of procarboxypeptidase Y |
| 3.4.23.25 | proproteinase A + H2O |
autocatalytic activation of proproteinase A |
| 3.4.23.25 | proproteinase A + H2O |
autoactivation of the enzyme yields a functional protein cleaved after Ser68, autoactivation can occur in rare situations when PrB is unable to activate PrA |
| 3.4.23.25 | proproteinase B + H2O |
maturation and activation of proproteinase B |
