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EC Number
Natural Substrates
Commentary (Nat. Sub.)
3.4.22.B28
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calpain 8/nCL-2 and calpain 9/nCL-4 constitute an active protease complex, G-calpain, in which both molecules are essential for activity, and that is involved in gastric mucosal defense. Calpains 8 and 9 are regulated differently from each other and from conventional calpains and, thus, have potentially important, specific functions in the gastrointestinal tract. Calpains 8 and 9 are molecular chaperones for each other, overview
3.4.22.B28
peptide + H2O
specific regulatory function of the enzyme in digestive tract
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