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Results 1 - 10 of 97 > >>
EC Number Natural Substrates Commentary (Nat. Sub.)
Display the word mapDisplay the reaction diagram Show all sequences 3.4.22.61alpha-fodrin + H2O -
Display the word mapDisplay the reaction diagram Show all sequences 3.4.22.61Atg3 protein + H2O -
Display the word mapDisplay the reaction diagram Show all sequences 3.4.22.61BH3-only protein Bid + H2O -
Display the word mapDisplay the reaction diagram Show all sequences 3.4.22.61BID + H2O a 15000 Da C-terminal frament and a 14000 Da N-terminal fragment are generated by caspase-8 cleavage at T58-/-D59. While full-length BID is localized in cytosol, truncated BID translocates to mitochondria and thus transduces apoptotic signals from cytoplasmic membrane to mitochondria. BID is a mediator of mitochondrial damage induced by Casp8
Display the word mapDisplay the reaction diagram Show all sequences 3.4.22.61Bid + H2O Bid is a caspase-8 substrate and that its cleavage can be crucial for CD95-induced apoptosis. Caspase-8-mediated cleavage of Bid into a pro-apoptotically active, truncated form provides the link between death receptor stimulation and mitochondrial apoptotic events
Display the word mapDisplay the reaction diagram Show all sequences 3.4.22.61Bid + H2O i.e. BH3 interacting domain death agonist
Display the word mapDisplay the reaction diagram Show all sequences 3.4.22.61Bid peptide + H2O -
Display the word mapDisplay the reaction diagram Show all sequences 3.4.22.61Bid peptide + H2O a specific caspase-8 substrate
Display the word mapDisplay the reaction diagram Show all sequences 3.4.22.61Bid peptide + H2O CTX III, from crude venom of Naja naja atra, inhibits proliferation of human leukemia K562 cells by G2/M phase arresting and apoptosis which is associated with the activation of caspase-8 and cytochrome c release as well as the p38 and c-Jun N-terminal protein kinase phosphorylation signaling pathway in vitro and in vivo, caspase-8-dependent Bid-Bax pathway, overview
Display the word mapDisplay the reaction diagram Show all sequences 3.4.22.61Bid protein + H2O -
Results 1 - 10 of 97 > >>