EC Number   |
Natural Substrates |
|---|
   3.4.21.84 | Limulus clotting factor B |
active factor Cbar selectively cleaves the Arg103-/-Ser104 and Ile124-/-Ile125 bonds in proenzyme factor B to form factor Bbar, which then activates proclotting enzyme to clotting enzyme. The resulting clotting enzyme acts on coagulogen, causing the formation of an insoluble coagulin gel |
| 3.4.21.84 | lipopolysaccharide + H2O |
binds a pathogen-associated LPS molecule to trigger a blood coagulation cascade |
| 3.4.21.84 | more |
- |
| 3.4.21.84 | more |
factor C is an initiator in the hemolymph coagulation system of horseshoe crab (Limulus polyphemus, Tachypleus tridentatus) |
| 3.4.21.84 | more |
factor C is essential for the endotoxin-mediated coagulation system |
| 3.4.21.84 | more |
blood coagulation cascade, which combines the function of hemostasis with immune response gainst gram-negative bacteria, besides blood coagulation and removal of endotoxin CrFC may be involved in cell signaling and protein-protein interaction |
| 3.4.21.84 | pro-factor B + H2O |
activation |
