EC Number   |
Natural Substrates |
|---|
   3.4.21.61 | alpha-mating factor + H2O |
cleavage of dibasic sites |
| 3.4.21.61 | CLC chloride channel + H2O |
cleavage in first intracellular loop at residues K136/R137 |
| 3.4.21.61 | corin + H2O |
activating processing of corin by enzyme PCSK6 |
| 3.4.21.61 | Killer toxin precursors + H2O |
cleavage of dibasic sites |
| 3.4.21.61 | low density lipoprotein receptor + H2O |
- |
| 3.4.21.61 | low density lipoprotein receptor + H2O |
degradation |
| 3.4.21.61 | low density lipoprotein receptor-related protein 1 + H2O |
degradation |
| 3.4.21.61 | more |
generates peptide hormone by specific processing of propeptides |
| 3.4.21.61 | more |
carries out specific endoproteolytic cleavage of proprotein and prohormone precursors in the secretory pathway, hydrolyzes ester and amide substrates |
| 3.4.21.61 | more |
transforming the precursors of biologically active agents into their functional forms, processing and conversion of prohormones |
