EC Number   |
Natural Substrates |
|---|
   3.4.21.60 | more |
enzyme acts on cell survival, regulating the expression of molecules as NO and avoiding cell death. Enzyme triggers release of interleukin 8, inhibits platelet activation and chemotaxis and causes uncoagulable blood by fibrinogen depletion |
| 3.4.21.60 | more |
the enzyme does not show fibrinogen-clotting, platelet-aggregating, fibrinogenolytic and factor X activating activities. Very low amidolytic activity as detected by the hydrolysis of the chromogenic substrates D-Phe-Pip-Arg-4-naphthyl amide and D-Val-Leu-Lys-4-naphthylamide |
| 3.4.21.60 | prothrombin + H2O |
- |
| 3.4.21.60 | prothrombin + H2O |
ecarin converts prothrombin to thrombin also if the prothrombin is not gamma-carboxylated |
| 3.4.21.60 | prothrombin + H2O |
cotiarinase is a snake venom serine proteinase that generated thrombin upon incubation with prothrombin, limited proteolysis of this protein to release prothrombin 1, fragment 1 and thrombin |
