EC Number   |
Natural Substrates |
|---|
   3.4.21.22 | D-Leu-Phg-Arg-4-nitroanilide + H2O |
- |
| 3.4.21.22 | factor X |
activation of factor X to factor Xa |
| 3.4.21.22 | Factor X + H2O |
- |
| 3.4.21.22 | Factor X + H2O |
the activation of factor X by factor IXa-factor VIIIa complex, known as the intrinsic tenase complex, results in the loss of a 55-residue activation peptide and subsequent formation of activated factor X |
| 3.4.21.22 | factor X + H2O |
gamma-carboxyglutamic acid, Gla-domains of vitamin K-dependent coagulation factors are essential for binding of phospholipid and for the activation raections such as factor X, the interaction of the Gla-domain with metal ions like Ca2+ is essential for its function |
| 3.4.21.22 | factor X + H2O |
a chymotrypsin homologue, and one of the gamma-carboxyglutamic acid-containing blood coagulation factors. The proenzyme factor IX is activated by factor XIa |
| 3.4.21.22 | factor X + H2O |
in the presence of FVIIIa (5 units/ml) at 37 °C |
| 3.4.21.22 | factor X + H2O |
factor IXa is a vitamin K-dependent blood coagulation factor that is essential for the amplification or consolidation phase of blood coagulation |
| 3.4.21.22 | factor X + H2O |
proteolytic activity, factor IXa acts as part of phosphocholine/phosphoserine vesicles interacting with factor VIIIa in the complex in a sodium-dependent manner, overview |
| 3.4.21.22 | factor X + H2O |
the enzyme acts in complex with factor VIIIa, FVIIIa deficiency causes the bleeding disorder hemaphilia A |
