EC Number   |
Natural Substrates |
|---|
   3.4.21.117 | beta-amyloid peptide + H2O |
degradation, the enzyme cleaves after both Phe residues within the core of Abeta42 in vitro, thereby inhibiting A? fibril formation and promoting the degradation of preformed fibrils |
| 3.4.21.117 | CYR61 + H2O |
- |
| 3.4.21.117 | E-cadherin + H2O |
kallikrein 7 degrades extracellular matrix proteins, and enhances pancreatic cancer cell invasion by shedding E-cadherin, overview |
| 3.4.21.117 | Fibronectin + H2O |
kallikrein degrades components of the extracellular matrix |
| 3.4.21.117 | midkine + H2O |
- |
| 3.4.21.117 | more |
enzyme is regulated by steroid hormones |
| 3.4.21.117 | more |
enzyme may contribute to tumor cell growth, tumor spread, and the metastatic potential of ovarian tumor cells |
| 3.4.21.117 | more |
AACC insertion in the stratum corneum chymotryptic enzyme gene may result in a change to activity of stratum corneum chymotryptic enzyme within the skin barrier. Stratum corneum chymotryptic enzyme could have an important role in the development of atopic dermatitis |
| 3.4.21.117 | more |
epidermal hyperproliferation and decreased skin barrier function in mice overexpressing stratum corneum chymotryptic enzyme |
| 3.4.21.117 | more |
gene expression might be involved in lung tumorigenesis |
