EC Number   |
Natural Substrates |
|---|
   3.4.21.10 | more |
digestion of zona pellucida by sperm, glycoprotein layer surrounding the oocyte |
| 3.4.21.10 | more |
lysis of Arg/Lys-X bonds |
| 3.4.21.10 | more |
possibly important for fertilization process, involved in the acrosome reaction, binding of spermatozoa to and penetration through the zona pellucida |
| 3.4.21.10 | more |
proacrosin involved in stereospecific sulfate binding that mediates the retention of post-acrosome reaction spermatozoa on the zona pellucida surface |
| 3.4.21.10 | more |
thought to fulfill several different roles in fertilization including that of a serine protease and in secondary zona pellucida binding |
| 3.4.21.10 | Nalpha-benzoyl-DL-arginine-4-nitroanilide + H2O |
- |
| 3.4.21.10 | proacrosin + H2O |
- |
| 3.4.21.10 | proacrosin + H2O |
acrosin autoactivates through an endoproteolytic cleavage at the N-terminus with subsequent conversion to the mature enzyme through C-terminus cleavages |
| 3.4.21.10 | proteinase-activated receptor-2 + H2O |
the enzyme may play additional role(s) in the fertilization process via the activation of PAR-2 on oocytes |
