EC Number   |
Natural Substrates |
|---|
   3.4.17.21 | N-acetyl-alpha L-aspartyl-L-glutamate + H2O |
- |
| 3.4.17.21 | N-acetyl-alpha-L-aspartyl-L-glutamate + H2O |
- |
| 3.4.17.21 | N-acetyl-Asp-Glu + H2O |
- |
| 3.4.17.21 | N-acetyl-L-aspartyl-L-glutamate + H2O |
- |
| 3.4.17.21 | poly-gamma-glutamate folate + H2O |
activity outside of the cell |
| 3.4.17.21 | folyl-poly-gamma-glutamate + H2O |
cleavage of the C-terminal glutamate |
| 3.4.17.21 | more |
cross-linking of cell surface PSMA with specific antibodies activates the small GTPases RAS and RAC1 and the MAPKs p38 and ERK1/2 in prostate carcinoma LNCaP cells via NF-kappaB activation, overview. Proliferation of LNCaP cells is inducible by interleukin-6, CCL5 or by cross-linking of PSMA |
| 3.4.17.21 | more |
enzyme inhibition depresses mossy fiber-CA3 synaptic transmission |
| 3.4.17.21 | N-acetyl-alpha-L-aspartyl-L-glutamate + H2O |
enzyme inhibition reduces acute neuronal degeneration and astrocyte damage following lateral fluid percussion traumatic brain injury |
| 3.4.17.21 | N-acetyl-alpha-L-aspartyl-L-glutamate + H2O |
enzyme regulation is mediated by glial glutamate and acetylcholine receptors in the nervous tissue |
