EC Number   |
Natural Substrates |
|---|
   3.1.4.45 | glycoprotein N-acetyl-D-glucosaminyl-phospho-D-mannose + H2O |
- |
| 3.1.4.45 | glycoprotein N-acetyl-D-glucosaminyl-phospho-D-mannose + H2O |
removes a covering N-acetylglucosamine from the mannose 6-phosphate recognition marker on lysosomal acid hydrolases |
| 3.1.4.45 | glycoprotein N-acetyl-D-glucosaminyl-phospho-D-mannose + H2O |
catalyzes a crucial step in lysosomal biogenesis, removes a covering N-acetylglucosamine from the mannose 6-phosphate recognition marker on lysosomal hydrolases |
| 3.1.4.45 | more |
acts on a variety of compounds with N-acetyl-D-glucosamine alpha-linked to phosphate group, including biosynthetic intermediates of the high mannose oligosaccharide components of some lysosomal enzymes |
| 3.1.4.45 | more |
catalyzes the second step in the formation of the mannose 6-phosphate recognition marker on lysosomal enzyme oligosaccharides |
| 3.1.4.45 | more |
removal of the GlcNAc moiety in the trans Golgi network to generate a phosphomonoester, second step of the post-translational modification of lysosomal enzymes with Man-6-P |
| 3.1.4.45 | more |
D-mannose 6-phosphate phosphodiesters are converted to phosphomonoester |
| 3.1.4.45 | N-[6-O-(N-acetyl-alpha-D-glucosaminyl)phospho-alpha-D-mannosyl]-[alpha-L-iduronidase]-L-asparagine + H2O |
- |
