EC Number |
Natural Substrates |
---|
3.1.4.4 | DNA + H2O |
endonuclease |
3.1.4.4 | more |
involved in wound-induced metabolism of polyunsaturated fatty acids |
3.1.4.4 | more |
PldA contributes to the ability of Pseudomonas aeruginosa PAO1 to persist in a chronic pulmonary infection model in rats |
3.1.4.4 | more |
5-[4-acridin-[9-ylamino]phenyl]-5-methyl-3-methylenedihydrofuran-2-one inhibits the formyl-Met-Leu-Phe-stimulated phospholipase D activity, mainly through the blockade of RhoA activation and degranulation |
3.1.4.4 | more |
activation of phospholipase D by 8-Br-cAMP occurs through a pathway involving Src, Ras, and ERK in human endometrial stromal cells |
3.1.4.4 | more |
alpha-adrenoreceptor activation increases phospholipase D activity |
3.1.4.4 | more |
constitutive cation channel activity in ear artery myocytes is mediated by diacylglycerol which is generated by phosphatidylcholine-phospholipase D via phosphatidic acid which represents a novel activation pathway of cation channels in vascular myocytes |
3.1.4.4 | more |
crosstalk between protein kinase A and C regulates phospholipase D and F-actin formation during sperm capacitation |
3.1.4.4 | more |
dependency of activation of protein kinase D on phospholipase D, phospholipase D could be a key molecule that links Rho/protein kinase C signaling to diacylglycerol for protein kinase D activation |
3.1.4.4 | more |
down-regulation of melanogenesis is mediated by phospholipase D2 but not by phospholipase D1 through turbiquitin proteasome-mediated degradation of tyrosinase. PLD2 may play an important role in regulating pigmentation in vivo |