EC Number   |
Natural Substrates |
|---|
    2.8.4.1 | 2-(methylthio)ethanesulfonate + N-(7-mercaptoheptanoyl)threonine 3-O-phosphate |
i.e. CoM and CoB |
| 2.8.4.1 | 2-(methylthio)ethansulfonate + N-(7-mercaptoheptanoyl)threonine 3-O-phosphate |
i.e. CoM and CoB |
| 2.8.4.1 | CH3-S-CoM + HS-CoB |
- |
| 2.8.4.1 | CH3-S-CoM + HS-CoB |
i.e. methyl-coenzyme M + coenzyme B |
| 2.8.4.1 | CH3-S-CoM + HS-CoB |
key step in the convertion of C1 substrates or acetate to methane thereby providing energy for the cell |
| 2.8.4.1 | CH3-S-CoM + HS-CoB |
MCR catalyzes the first proposed step in anaerobic methane oxidation and terminal step in methanogenesis by using N-7-mercaptoheptanolyl-threonine phosphate, i.e. CoB-SH. as the two-electron donor to reduce 2-(methylthiol)-ethane sulfonate, i.e. methyl-SCoM, to methane, and producing the heterodisulfide, CoBS-SCoM |
| 2.8.4.1 | CH3-S-CoM + HS-CoB |
MCR catalyzes the methane-forming step in methanogenic archaea |
| 2.8.4.1 | CH3-S-CoM + HS-CoB |
HS-CoB is N-(7-mercaptoheptanoyl)-L-threonine 3-O-phosphate |
| 2.8.4.1 | CH3-S-CoM + HS-CoB |
i.e. N-7-mercaptoheptanoylthreonine phosphate, Ni(III)-methyl is an intermediate in methane formation |
| 2.8.4.1 | CH3-S-CoM + SH-CoB |
- |
