EC Number |
Natural Substrates |
---|
2.7.7.13 | diphosphate + GDP-mannose |
- |
2.7.7.13 | GTP + alpha-D-mannose 1-phosphate |
- |
2.7.7.13 | GTP + alpha-D-mannose 1-phosphate |
enzyme regulates GDP-D-mannose synthesis through feedback inhibition |
2.7.7.13 | GTP + alpha-D-mannose 1-phosphate |
enzyme of alginate biosynthetic pathway |
2.7.7.13 | GTP + alpha-D-mannose 1-phosphate |
overexpression leads to an increase in cellular GDPmannose levels |
2.7.7.13 | GTP + alpha-D-mannose 1-phosphate |
regulation of the enzyme expression, overview |
2.7.7.13 | more |
truncated GDP-mannose pyrophosphorylase domain of the whole length enzyme shows almost 100fold less sugar nucleotidyltransferase activity with only GTP and mannose 1-phosphate as substrates. The enzyme accepts all five naturally occurring NTPs (ATP, CTP, GTP, dTTP and UTP) and a range of sugar-1-phosphates (glucose-, mannose-, galactose-, glucosamine-, N-acetylglucosamine- and fucose-1-phosphate) |
2.7.7.13 | more |
repression of GMPP in yeast leads to phenotypes including hyphal lysis, defective cell wall, and failure of polarized growth and branching site selection, and cell separation |
2.7.7.13 | more |
the enzyme of Burkholderia cenocepacia, encoded by gene bceA, is bifunctional exhibiting phosphomannose isomerase and GDP-D-mannose pyrophosphorylase activities |
2.7.7.13 | more |
the enzyme of Burkholderia cepacia, encoded by gene bceA, is bifunctional exhibiting phosphomannose isomerase and GDP-D-mannose pyrophosphorylase activities |