EC Number   |
Natural Substrates |
|---|
    2.7.2.8 | ATP + N-acetyl-L-glutamate |
- |
| 2.7.2.8 | ATP + N-acetyl-L-glutamate |
key enzyme in regulation of arginine biosynthesis |
| 2.7.2.8 | ATP + N-acetyl-L-glutamate |
enzyme synthesis not repressed by exogenous L-arginine or its precursors |
| 2.7.2.8 | ATP + N-acetyl-L-glutamate |
second enzyme of arginine biosynthesis |
| 2.7.2.8 | ATP + N-acetyl-L-glutamate |
NAGK catalyzes the second step of arginine biosynthesis. In Pseudomonas aeruginosa, this step is rate limiting, and feedback regulated and sigmoidally inhibited by arginine |
| 2.7.2.8 | more |
NAGK strongly interacts with PII protein only in the presence of Mg-ATP, this process is reversed by 2-oxoglutarate |
| 2.7.2.8 | more |
NAGK interacts with PII protein |
