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Results 1 - 3 of 3

EC Number	Natural Substrates	Commentary (Nat. Sub.)
2.7.1.83	ATP + pseudouridine	involved in utilization of pseudouridine as pyrimidine source by E. coli pyrimidine auxotrophs
2.7.1.83	ATP + pseudouridine	-
2.7.1.83	ATP + pseudouridine	two enzymes are involved in the metabolism of pseudouridine in uropathogenic Escherichia coli, the principal agent of urinary tract infections in humans. The first enzyme, coded by the gene yeiC, specifically phosphorylates pseudouridine to pseudouridine 5'-phosphate. yeiC- mutants are unable to metabolize pseudouridine, in contrast to wild-type Escherichia coli UTI89. The second enzyme, encoded by the gene yeiN (EC 4.2.1.70) belonging to the same operon as yeiC, catalyzes the conversion of pseudouridine 5'-phosphate to uracil and ribose 5-phosphate in a divalent cation-dependent manner

Results 1 - 3 of 3

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Release 2023.1 (January 2023)