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EC Number
Natural Substrates
Commentary (Nat. Sub.)
2.7.1.145
ATP + 2'-deoxyadenosine
-
2.7.1.145
ATP + 2'-deoxycytidine
-
2.7.1.145
ATP + 2'-deoxyguanosine
-
2.7.1.145
ATP + 2'-deoxynucleoside
-
2.7.1.145
ATP + 2'-deoxyribonucleoside
-
2.7.1.145
ATP + 2'-deoxythymidine
-
2.7.1.145
ATP + a 2'-deoxyribonucleoside
-
2.7.1.145
ATP + thymidine
-
2.7.1.145
more
enzyme evolution by gene duplication of a progenitor kinase
2.7.1.145
more
enzyme shows broad substrate specificity, this enzyme specificity-type is the earliest in evolution probably encoded by the so-called dCK/dGK/TK2-like gene, several duplications of the progenitor gene are the reason for evolutionary occurring of nucleoside kinases with strict substrate specificities in other organism, phylogenetic tree, insects lost all but 1 nucleotide kinase, overview
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