EC Number |
Natural Substrates |
---|
2.5.1.58 | (2E,6E)-farnesyl diphosphate + (protein)-L-cysteine |
- |
2.5.1.58 | (2E,6E)-farnesyl diphosphate + [H Ras]-L-cysteine |
- |
2.5.1.58 | (2E,6E)-farnesyl diphosphate + [K Ras]-L-cysteine |
- |
2.5.1.58 | (2E,6E)-farnesyl diphosphate + [N Ras]-L-cysteine |
- |
2.5.1.58 | (2E,6E)-farnesyl diphosphate + [protein]-L-cysteine |
- |
2.5.1.58 | (2E,6E)-farnesyl diphosphate + [Rho]-L-cysteine |
- |
2.5.1.58 | farnesyl diphosphate + protein-cysteine |
- |
2.5.1.58 | farnesyl diphosphate + protein-cysteine |
process required for the transforming activity of oncogenic variants of Ras, making enzyme a prime target for anticancer therapeutics |
2.5.1.58 | farnesyl diphosphate + protein-cysteine |
process necessary for the subcellular localisation of substrate to the plasma membrane |
2.5.1.58 | farnesyl diphosphate + protein-cysteine |
enzyme responsible for catalysing isoprene lipid modifications |