EC Number |
Natural Substrates |
---|
2.4.2.3 | 5-methyluridine + phosphate |
- |
2.4.2.3 | more |
the enzyme is regulated by multiple lipid-sensing nuclear receptors, gene expression is diurnally regulated |
2.4.2.3 | more |
catalyzes the first step of uridine degradation to beta-alanine in liver |
2.4.2.3 | more |
the enzyme also activates pyrimidine-containing drugs, including 5-fluorouracil, mechanism of the enzyme-drug interaction, overview |
2.4.2.3 | more |
UPP catalyzes the reversible phosphorolysis of uracil ribosides and analogous compounds to their respective nucleobases and ribose-1-phosphate, structural mechanisms, overview |
2.4.2.3 | pyrimidine nucleoside + phosphate |
most pyrimidine nucleosides except for 4-amino-substituted species like deoxycytidine |
2.4.2.3 | thymidine + phosphate |
- |
2.4.2.3 | uracil + alpha-D-ribose 1-phosphate |
- |
2.4.2.3 | uracil + alpha-D-ribose 1-phosphate |
uridine prevents the glucose deprivation-induced death of immunostimulated astrocytes via the action of uridine phosphorylase |
2.4.2.3 | uridine + phosphate |
- |