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Results 1 - 10 of 13 > >>
EC Number Natural Substrates Commentary (Nat. Sub.)
Display the word mapDisplay the reaction diagram Show all sequences 2.4.2.12more FK866, a highly specific noncompetitive inhibitor of nicotinamide phosphoribosyltransferase, represents a novel mechanism for induction of tumor cell apoptosis in tissues with a high demand for NAD+
Display the word mapDisplay the reaction diagram Show all sequences 2.4.2.12more NMPRTase is a crucial enzyme in the salvage pathway of NAD+ biosynthesis and has important functions in regulating NAD+ levels in cells undergoing substantial NAD+ turnover
Display the word mapDisplay the reaction diagram Show all sequences 2.4.2.12more rate-limiting enzyme for NAD+ salvage from nicotinamide. Replicative senescence of smooth muscle cells is preceded by a marked decline in the expression and activity of Nampt. Nampt is a longevity protein that can add stress-resistant life to human smooth muscle cells by optimizing SIRT1-mediated p53 degradation
Display the word mapDisplay the reaction diagram Show all sequences 2.4.2.12more visfatin mimics insulin signaling by binding to the insulin receptor with an affinity similar to that of insulin and does not share the binding site with insulin on the insulin receptor
Display the word mapDisplay the reaction diagram Show all sequences 2.4.2.12nicotinamide + 5-phospho-alpha-D-ribose 1-diphosphate -
Display the word mapDisplay the reaction diagram Show all sequences 2.4.2.12nicotinamide + 5-phospho-alpha-D-ribose 1-diphosphate first step in NAD synthesis from nicotinamide
Display the word mapDisplay the reaction diagram Show all sequences 2.4.2.12nicotinamide + 5-phospho-alpha-D-ribose 1-diphosphate pre-B-cell colony enhancing factor
Display the word mapDisplay the reaction diagram Show all sequences 2.4.2.12nicotinamide + 5-phospho-alpha-D-ribose 1-diphosphate key enzyme in the regulation of NAD+ biosynthesis from the natural precursor nicotinamide
Display the word mapDisplay the reaction diagram Show all sequences 2.4.2.12nicotinamide + 5-phospho-alpha-D-ribose 1-diphosphate key enzyme in the regulation of NAD+ biosynthesis, regulates the silent regulator protein 2, i.e. Sir2, activity, the enzyme has a metabolic regulatory function by up- and downregulation of proteins, overview
Display the word mapDisplay the reaction diagram Show all sequences 2.4.2.12nicotinamide + alpha-D-5-phosphoribosyl 1-diphosphate -
Results 1 - 10 of 13 > >>