EC Number |
Natural Substrates |
---|
2.4.1.244 | more |
the enzyme could transfer GalNAc residues, producing N,N'-diacetylgalactosediamine structures at least in N-glycans and probably in both N- and O-glycans |
2.4.1.244 | more |
flies mutant for beta4GalNAcTA are viable and fertile but display behavioral phenotypes suggestive of essential roles for GalNAc-beta1,4-GlcNAc containing glycoconjugates in neuronal and/or muscular function |
2.4.1.244 | more |
flies mutant for beta4GalNAcTB are viable and display no evident morphological or behavioral phenotypes |
2.4.1.244 | UDP-N-acetyl-D-galactosamine + N-acetyl-beta-D-glucosaminyl-R group |
beta4Gal-NAcTA has at least three distinct, tissue-specific roles in neurons and muscles. Substrates are present in both neural and muscle cells that require glycosylation by beta4GalNAcTA for normal function |
2.4.1.244 | UDP-N-acetyl-D-galactosamine + N-acetyl-beta-D-glucosaminyl-R group |
beta4GalNAcTA contributs to the synthesis of the GalNAcbeta1,4GlcNA structure in vivo and may play a role in the physiological or neuronal development of Drosophila |