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Results 1 - 10 of 17 > >>
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EC Number Natural Substrates Commentary (Nat. Sub.)
Display the word mapDisplay the reaction diagram Show all sequences 2.4.1.155more down regulation of N-acetylglucosaminyltransferase V facilitates all-transretinoic acid to induce apoptosis of human hepatocarcinoma cells
Display the word mapDisplay the reaction diagram Show all sequences 2.4.1.155more GnT-V is cleaved at the transmembrane region by gamma-secretase, and this might control tumor angiogenesis
Display the word mapDisplay the reaction diagram Show all sequences 2.4.1.155more N-acetylglucosaminyltransferase V is a key enzyme in the formation of branching of asparagine-linked oligosaccharides and is strongly linked to tumor invasion and metastasis. Blocking of GnT-V expression impairs functions of chaperones and N-glycan-synthesizing enzymes, which causes unfolded protein response in vivo
Display the word mapDisplay the reaction diagram Show all sequences 2.4.1.155more GnT-V can partially compensate for GnT-Vb(IX) activity in vivo
Display the word mapDisplay the reaction diagram Show all sequences 2.4.1.155more the MCAM glycoprotein, which is a biomarker of cutaneous melanoma, as a potential target for overexpressed glycosyltransferases
Display the word mapDisplay the reaction diagram Show all sequences 2.4.1.155UDP-N-acetyl-alpha-D-glucosamine + beta-D-GlcNAc-(1->2)-[beta-D-GlcNAc-(1->4)]-alpha-D-Man-(1->3)-[beta-D-GlcNAc-(1->2)-alpha-D-Man-(1->6)]-beta-D-Man-(1->4)-beta-D-GlcNAc-(1->4)-beta-D-GlcNAc-N-Asn-[protein] -
Display the word mapDisplay the reaction diagram Show all sequences 2.4.1.155UDP-N-acetyl-alpha-D-glucosamine + beta-D-GlcNAc-(1->2)-[beta-D-GlcNAc-(1->4)]-alpha-D-Man-(1->3)-[beta-D-GlcNAc-(1->2)-alpha-D-Man-(1->6)]-beta-D-Man-(1->4)-beta-D-GlcNAc-(1->4)-beta-D-GlcNAc-N-Asn-[TIMP-1] -
Display the word mapDisplay the reaction diagram Show all sequences 2.4.1.155UDP-N-acetyl-D-glucosamine + 6-(2-[N-acetyl-beta-D-glucosaminyl]-alpha-D-mannosyl)-beta-D-mannosyl-R -
Display the word mapDisplay the reaction diagram Show all sequences 2.4.1.155UDP-N-acetyl-D-glucosamine + 6-(2-[N-acetyl-beta-D-glucosaminyl]-alpha-D-mannosyl)-beta-D-mannosyl-R catalyzes the formation of beta-1-6 GlcNAc branches on asparagine-linked oligosaccharides, which is directly linked to tumorigenesis
Display the word mapDisplay the reaction diagram Show all sequences 2.4.1.155UDP-N-acetyl-D-glucosamine + 6-(2-[N-acetyl-beta-D-glucosaminyl]-alpha-D-mannosyl)-beta-D-mannosyl-R GnTIII competes with GnT-V for the modification of integrin alpha3 subunit in living cells. This competition results in the inhibition of alpha3beta1 integrin-mediated cell migration induced by GnT-V
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