EC Number |
Natural Substrates |
---|
2.4.1.144 | more |
- |
2.4.1.144 | UDP-N-acetyl-alpha-D-glucosamine + beta-D-GlcNAc-(1->2)-alpha-D-Man-(1->3)-[beta-D-GlcNAc-(1->2)-alpha-D-Man-(1->6)]-beta-D-Man-(1->4)-beta-D-GlcNAc-(1->4)-beta-D-GlcNAc-N-Asn-[Notch receptor] |
- |
2.4.1.144 | UDP-N-acetyl-alpha-D-glucosamine + beta-D-GlcNAc-(1->2)-alpha-D-Man-(1->3)-[beta-D-GlcNAc-(1->2)-alpha-D-Man-(1->6)]-beta-D-Man-(1->4)-beta-D-GlcNAc-(1->4)-beta-D-GlcNAc-N-Asn-[protein] |
- |
2.4.1.144 | UDP-N-acetyl-D-glucosamine + (N-acetyl-beta-D-glucosaminyl-1,2-alpha-D-mannosyl-1,3)-(N-acetyl-beta-D-glucosaminyl-1,2-alpha-D-mannosyl-1,6)-beta-D-mannosyl-1,4-N-acetyl-beta-D-glucosaminyl-R |
- |
2.4.1.144 | UDP-N-acetyl-D-glucosamine + beta-D-mannosyl-R |
- |
2.4.1.144 | more |
beta1,4-N-acetylglucosaminyltransferase III potentiates beta1 integrin-mediated neuritogenesis induced by serum deprivation in Neuro2a cells |
2.4.1.144 | more |
biosynthetic pathway of the core structures of Asn-linked sugar chains, overview |
2.4.1.144 | more |
cell-cell interaction-dependent regulation of N-acetylglucosaminyltransferase III and the bisected N-glycans in GE11 epithelial cells |
2.4.1.144 | UDP-N-acetyl-D-glucosamine + (N-acetyl-beta-D-glucosaminyl-1,2-alpha-D-mannosyl-1,3)-(N-acetyl-beta-D-glucosaminyl-1,2-alpha-D-mannosyl-1,6)-beta-D-mannosyl-1,4-N-acetyl-beta-D-glucosaminyl-R |
enzyme plays an important role in the progression of preneoplastic foci to primary hepatoma |
2.4.1.144 | UDP-N-acetyl-D-glucosamine + beta-D-mannosyl-R |
GnT-III catalyzes the formation of a bisecting GlcNAc structure in N-glycans, resulting in the suppression of metastasis. The priority of GnT-III for the modification of the integrin alpha3 subunit may be an explanation for why GnT-III inhibits GnT-V-induced cell migration. TGnT-III and GnT-V can competitively modify the same target glycoprotein and furthermore positively or negatively regulate its biological functions |