EC Number |
Natural Substrates |
---|
2.3.1.6 | acetyl-CoA + choline |
- |
2.3.1.6 | acetyl-CoA + choline |
synthesis of the neurotransmitter acetylcholine |
2.3.1.6 | acetyl-CoA + choline |
synthesis of the neurotransmitter acetylcholine that is essential for the development and neuronal activities of the cholinergic systems involved in many fundamental brain functions |
2.3.1.6 | acetyl-CoA + choline |
synthesis of the neurotransmitter acetylcholine, deficiency in ChAT involved in several neurological and psychiatric disorders |
2.3.1.6 | acetyl-CoA + choline |
synthesis of the neurotransmitter acetylcholine, mutations in ChAT causes congenital neuromuscular disorders |
2.3.1.6 | acetyl-CoA + choline |
choline taken up by OCTs or derived from the plasma membrane is also utilized for acetylcholine synthesis in both cholinergic neurons and nonneuronal cholinergic cells, such as lymphocytes |
2.3.1.6 | acetyl-CoA + choline |
formation of acetylcholine in cholinergic neurons largely depends on both the levels of choline being transported into the cells from the extracellular space and the activity of ChAT, kinetics of choline uptake in the SK-N-SH cells |
2.3.1.6 | more |
pilocarpine-induced seizures produce alterations on choline acetyltransferase and acetylcholinesterase activities and deficit memory in rats, overview |